#drug
- Abuse does not invalidate just use — A fundamental principle in bioethics, pharmacovigilance, and clinical toxicology stating that 'a conclusion from the abuse of a thing to its use is not valid'. In medicine, it means that the prohibition or condemnation of a useful drug or medical treatment (e.g., opioids for severe pain) is not justified simply because some patients or individuals abuse it.
- Administration — The act of administering and its result; the management, direction, organization, and supervision of the activities of a legal entity or assets. In medicine, it represents the act of introducing a medicinal substance into the organism, and in computing, the set of maintenance and system configuration operations.
- Aeron — A complex pharmaceutical preparation, in tablet form, historically used for preventing and combating motion sickness (kinetosis), seasickness, car sickness, or air sickness. Its chemical composition was based on a stable combination of scopolamine and hyoscyamine salts, having a direct effect of inhibiting cholinergic receptors and reducing the excitability of the vestibular apparatus.
- Aerosolization — The act of aerosolizing and its result; a physical, mechanical, or experimental process through which a liquid or solid substance is transformed into microscopic particles suspended in air or a gaseous medium. In medicine, it represents the fundamental operating technique of nebulizers to allow efficient drug delivery directly into the pulmonary alveoli.
- Agonist — A chemical substance, drug, or hormone that binds to a specific cellular receptor and triggers a biological response, mimicking the action of an endogenous compound; in muscle physiology, it designates a muscle whose contraction directly produces a specific movement.
- Agranulocytosis — An acute and severe hematological condition characterized by a drastic reduction or near-complete disappearance of granulocytes (primarily neutrophils) in the peripheral blood, dropping below 500 per microliter. It leaves the body highly vulnerable to life-threatening infections.
- Aldrofan — A historical or regional commercial name for a pharmaceutical compound utilized in treating acute respiratory disorders or as an adjuvant agent in dermatological therapy; in a generic sense, it represents a specific chemical formulation stored as tablets or stabilized solution according to industrial pharmacological standards.
- Allopathic — Relating to physicians, treatment methods, or pharmaceutical products: pertaining to allopathy or conventional scientific medicine; a physician who practices evidence-based medicine, utilizing chemical substances or active procedures that produce effects opposite or contrary to the symptoms of the disease being treated (following the contraria contrariis curantur principle). This structural system differs fundamentally from homeopathy or complementary empirical practices.
- Ambazone — A synthetic organic chemical compound of the thiosemicarbazone class, used in medicine as a potent local antiseptic and bacteriostatic agent, especially for treating acute infections of the oral cavity and pharynx. It acts by inhibiting pathogen replication.
- Amebicide — A chemical substance or medication that destroys amoebae, particularly the active or cystic forms of Entamoeba histolytica; as an adjective, it describes the structural pharmacological property of a therapeutic agent capable of eliminating an amoebic infestation.
- Amoebicide — An orthographic variant of the term 'amibicid'; a chemical substance or medicinal agent with a specific molecular structure capable of destroying amoebae and single-celled parasites embedded in human or animal tissues. This type of compound acts by inhibiting vital metabolic pathways of the protozoans.
- Amidazine — An alternative pharmacological term or historical commercial name used to designate a medicinal compound from the class of chemotherapeutic or antitubercular agents, structurally closely related to pyrazinamide derivatives or hydrazides. This therapeutic agent acts by interfering with fatty acid synthesis in the bacterial cell wall, administered in complex clinical regimens to neutralize pathogens resistant to conventional antibiotics.
- Amidopyrine — A medicinal compound from the pyrazolone class, historically used as a potent analgesic, antipyretic, and anti-inflammatory agent, chemically known as aminophenazone. Although it possesses high structural efficiency in combating fever and acute pain, its modern clinical use has been severely restricted or banned in most countries due to the documented risk of inducing severe agranulocytosis and the formation of carcinogenic nitrosamines in the stomach.
- Aminophenazone — An organic compound of the pyrazolone class, historically widely used as a drug with potent analgesic, antipyretic, and anti-inflammatory properties (also known as pyramidon). Due to its major structural risk of causing severe agranulocytosis and its carcinogenic potential through the formation of nitrosamines, its clinical use has been banned or severely restricted in modern medicine.
- Amoebicide — Destroying amoebae (amebae), especially the Entamoeba histolytica species responsible for amebic dysentery; a drug, chemical substance, or therapeutic agent used to destroy these parasitic protozoa. In pharmacology, these substances are divided into luminal amoebicides (active in the intestine) and tissue amoebicides (active in the liver or other organs).
- Amoxicillin — A semisynthetic antibiotic substance of the beta-lactam class, derived from penicillin, featuring a broad spectrum of antimicrobial activity against Gram-positive and Gram-negative bacteria. It acts by inhibiting bacterial cell wall synthesis during replication, being widely used in clinical practice to treat acute respiratory, urinary, cutaneous, or otorhinolaryngological infections.
- Ampicidul — The definite articulated form of the neuter noun 'ampicid', a historical or regional commercial name assigned to an antibiotic medication based on ampicillin, utilized for destroying and inhibiting the growth of a wide range of pathogenic bacteria. As a bactericide from the penicillin group, it structurally acts by blocking bacterial cell wall synthesis, being prescribed in treating sensitive acute respiratory, urinary, and gynecological infections.
- Ampicillin — A semi-synthetic antibiotic substance from the penicillin group, featuring a broad spectrum of activity, acid-stable but inactivated by beta-lactamases; it is widely utilized in medicine to treat various bacterial infections caused by susceptible microorganisms, acting by inhibiting bacterial cell wall synthesis during replication. It represents one of the most essential antimicrobial drugs included in fundamental therapeutic lists globally.
- Anadol — An historical commercial name attributed to an analgesic and antipyretic pharmaceutical preparation (based on aminophenol derivatives or related substances), structurally used in the past to relieve moderate pain and reduce febrile states. In a broader toxicological or chemical sense, the term can be encountered as a root or variant in the nomenclature of certain synthetic analgesic compounds studied for their effects on central nervous system receptors.
- Anaphoresis — A structural physicochemical phenomenon represented by the movement of negatively charged colloidal particles or ions (anions) within a solution or suspension toward the positive electrode (anode) under the influence of an external electric field. In medicine and dermatology, this form of electrophoresis is utilized therapeutically for the transcutaneous introduction of negatively charged drugs or ions directly into tissues, facilitating precise localized treatments.