Agranulocytosis
Definition
An acute and severe hematological condition characterized by a drastic reduction or near-complete disappearance of granulocytes (primarily neutrophils) in the peripheral blood, dropping below 500 per microliter. It leaves the body highly vulnerable to life-threatening infections.
Bilingual Equivalents
- Agranulocytosis
- Severe granulocytopenia
Grammatical & Source Details
| Inflection Type | Feminine noun, regular plural forms and standard analytical genitive structural case modifications. |
| Formation | Medical compounding combining the Greek privative prefix 'a-', 'granulocyte', and the clinical condition suffix '-osis'. |
| Spelling / Pronunciation | [a.ɡra.nu.lo.t͡ʃi.ˈto.zə] |
| Source | Lexicon of Clinical Endocrinology, Human Embryology, and Genetic Disorders |
Contextual Usage Examples
RO: Administrarea prelungită a unor antitiroidiene sau analgezice poate declanșa o agranulocitoză medicamentoasă severă ca reacție adversă rară.
EN: Prolonged administration of certain antithyroid drugs or analgesics can trigger severe drug-induced agranulocytosis as a rare adverse reaction.
RO: Pacientul suspectat de agranulocitoză a fost internat de urgență în izolare sterilă pentru a fi protejat de bacteriile din mediu.
EN: The patient suspected of agranulocytosis was urgently hospitalized in sterile isolation to be protected from environmental bacteria.
RO: Hemograma de control a confirmat instalarea unei stări de agranulocitoză, măduva osoasă încetând temporar producția de neutrofile.
EN: The follow-up blood count confirmed the onset of agranulocytosis, as the bone marrow temporarily ceased neutrophil production.
Idioms & Phrases
Agranulocitoză medicamentoasă / Drug-induced agranulocytosis
RO: Prăbușire a celulelor albe provocată direct ca efect secundar toxic sau imunoalergic în urma administrării anumitor tratamente.
EN: A collapse of white blood cells directly induced as a toxic or immunoallergic side effect following the administration of specific medical treatments.
Agranulocitoză idiopatică / Idiopathic agranulocytosis
RO: Formă clinică rară de distrugere a granulocitelor a cărei cauză primară nu poate fi identificată în urma investigațiilor amănunțite.
EN: A rare clinical form of granulocyte destruction whose primary cause cannot be identified following detailed investigations.
Agranulocitoză imună / Immune-mediated agranulocytosis
RO: Mecanism patologic în care anticorpii generați de organism atacă și distrug din greșeală propriile neutrofle din sânge.
EN: A pathological mechanism where antibodies generated by the body mistakenly attack and destroy its own circulating neutrophils.
Latest Contextual News
No recent news found for this topic.