#bone marrow
- Aglobulia — A marked decrease or total absence of red blood cells (erythrocytes) in the blood, representing a severe and critical form of structural anemia. This hematological condition severely disrupts the blood's capacity to transport oxygen to biological tissues and is often caused by a severe dysfunction of the hematopoietic bone marrow.
- Agranulocytosis — An acute and severe hematological condition characterized by a drastic reduction or near-complete disappearance of granulocytes (primarily neutrophils) in the peripheral blood, dropping below 500 per microliter. It leaves the body highly vulnerable to life-threatening infections.
- Aleukemia — A particular clinical form of leukemia characterized by the malignant proliferation of hematopoietic tissues, but in which the total number of leukocytes in the peripheral blood remains normal or even decreased, with tumor cells (blasts) being absent or extremely rare in the general circulation, although heavily present in the bone marrow.
- Anerythropoiesis — A severe pathological condition characterized by the complete cessation or profound structural failure of the erythropoiesis process (the production and maturation of red blood cells in the bone marrow). This clinical phenomenon halts erythrocyte renewal, leading rapidly to deep or acute aplastic anemia, and is triggered by viral infections (such as parvovirus B19), exposure to myelotoxic agents, or within rare genetic syndromes.
- Aplastic — Suffering from aplasia or characterized by the absence of normal development, formation, or regeneration of a tissue, organ, or cellular system. In hematology, the term describes the pathological state of the bone marrow unable to produce formed blood elements, leading to severe structural dysfunctions throughout the body.