Aplastic
Definition
Suffering from aplasia or characterized by the absence of normal development, formation, or regeneration of a tissue, organ, or cellular system. In hematology, the term describes the pathological state of the bone marrow unable to produce formed blood elements, leading to severe structural dysfunctions throughout the body.
Bilingual Equivalents
- Aplastic
- Non-regenerative
Grammatical & Source Details
| Inflection Type | Variable adjective with regular masculine, feminine, and clinical plural variations. |
| Formation | Derived from French 'aplastique', incorporating the privative prefix 'a-' and the Greek root for formation or molding. |
| Spelling / Pronunciation | [a.ˈplas.tik] |
| Source | Global Lexicon of Advanced Clinical Pathologies and Histology Standards |
Contextual Usage Examples
RO: Pacientul diagnosticat cu un sindrom aplastic sever a fost internat de urgență pentru o transfuzie masivă de trombocite.
EN: The patient diagnosed with a severe aplastic syndrome was urgently hospitalized for a massive platelet transfusion.
RO: Medicul a explicat că un țesut aplastic nu mai posedă capacitatea fiziologică de a se autoregenera după un traumatism.
EN: The doctor explained that an aplastic tissue no longer possesses the physiological capacity to self-regenerate after a trauma.
RO: Expunerea prelungită la radiații toxice poate provoca un stadiu aplastic la nivelul celulelor stem din organism.
EN: Prolonged exposure to toxic radiation can induce an aplastic stage within the stem cells of the organism.
Idioms & Phrases
Anemie aplastică / Aplastic anemia
RO: Afecțiune hematologică rară și gravă în care măduva osoasă nu mai produce suficiente celule sanguine vitale.
EN: A rare and serious hematological condition in which the bone marrow fails to produce enough vital blood cells.
Măduvă aplastică / Aplastic bone marrow
RO: Stare patologică a țesutului hematopoietic care prezintă o depleție masivă de celule precursoare în favoarea grăsimii.
EN: A pathological state of the hematopoietic tissue showing a massive depletion of precursor cells in favor of fat.
Viciu aplastic / Aplastic structural defect
RO: Defect congenital de formare a unui organ, determinat de oprirea precoce a diviziunii celulare în faza embrionară.
EN: A congenital defect in the formation of an organ, caused by the early cessation of cell division during the embryonic phase.
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