DEX » Romanian Language Etymological Dictionary » acromegalie

Acromegaly

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feminine noun (medicine / endocrinology)

Definition

A chronic neuroendocrine disease caused by a pathological hypersecretion of growth hormone (somatotropin) and insulin-like growth factor (IGF-1) in adulthood, after the closure of epiphyseal growth plates. The condition is characterized by the exaggerated enlargement of skeletal extremities (hands, feet), hypertrophy of facial bones (prognatism, prominent brow ridges), soft tissue thickening, macroglossia, and secondary severe cardiac or metabolic dysfunctions.

Bilingual Equivalents

  • Acromegaly
  • Pituitary gigantism (related)

Grammatical & Source Details

Inflection Type Feminine noun used strictly in the singular form within clinical and structural layouts.
Formation Neologistic borrowing via French 'acromégalie', rooted in the Greek terms for extremities and largeness.
Spelling / Pronunciation [a.kro.me.ga.ˈli.e]
Source Lexicon of Pituitary Disorders and Structural Endocrinology

Contextual Usage Examples

RO: Diagnosticul precoce de acromegalie este esențial pentru prevenirea complicațiilor cardiovasculare ireversibile.

EN: Early diagnosis of acromegaly is essential to prevent irreversible cardiovascular complications.

RO: Majoritatea cazurilor de acromegalie sunt cauzate de o tumoare benignă situată la nivelul glandei hipofize.

EN: Most cases of acromegaly are caused by a benign tumor located within the pituitary gland.

RO: Tratamentul pentru acromegalie poate include excizia chirurgicală a adenomului sau terapie medicamentoasă cu analogi de somatostatină.

EN: Treatment for acromegaly may include surgical excision of the adenoma or drug therapy with somatostatin analogs.

Idioms & Phrases

Diagnostic de acromegalie / Diagnosis of acromegaly

RO: Protocol clinic ce implică dozarea hormonilor serici și testul de toleranță la glucoză orală pentru confirmarea bolii.

EN: A clinical protocol involving serum hormone assays and an oral glucose tolerance test to confirm the disease.

Acromegalie dobândită / Acquired acromegaly

RO: Dezvoltare patologică a extremităților apărută în perioada de adult din cauza evoluției unei formațiuni tumorale secretante.

EN: A pathological development of the extremities appearing in adulthood due to the progression of a secreting tumor mass.

Manifestări clinice în acromegalie / Clinical manifestations in acromegaly

RO: Ansamblul modificărilor somatice și metabolice, precum cefaleea, transpirațiile excesive și tulburările vizuale cauzate de compresie.

EN: The set of somatic and metabolic changes, such as headaches, excessive sweating, and visual disturbances caused by compression.

Keywords

#acromegalie #acromegaly #endocrinology #growth hormone #pituitary adenoma #medical dictionary #igf-1 excess #skeletal hypertrophy
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