#immune response
- Agranulocyte — A type of leukocyte (white blood cell) characterized by the absence of specific granules in its cytoplasm and a non-lobed nucleus; agranulocytes include lymphocytes and monocytes, playing a vital role in adaptive immunity.
- Allergid — A secondary cutaneous eruption, of an allergic or inflammatory nature, appearing on the skin as a distant immune response to a primary infectious focus (bacterial, fungal, or parasitic) in the body, without the original pathogen being present in the secondary dermatological lesions. Structurally, allergids (such as mycids or tuberculids) reflect a cell-mediated dermo-epidermal hypersensitivity reaction.
- Anamnestic — Pertaining to anamnesis, referring to the clinical data and medical history gathered directly from the patient or their companions; based on medical history. In semiology, it describes a criterion, clue, or information obtained through dialogue, essential for guiding the diagnosis before conducting the physical examination or paraclinical investigations. In immunology, the anamnestic response represents the rapid and intense secondary reaction of the immune system upon re-exposure to an already known antigen.
- Aneosinophilia — A severe form of hematological alteration characterized by the total and complete absence of eosinophil granulocytes in peripheral blood, detected through a complete blood count with a differential white blood cell count. This structural clinical phenomenon is frequently associated with the acute stages of severe bacterial infections, septic shock, or as a secondary adverse reaction following prolonged glucocorticoid administration, reflecting a transient collapse of specific immunity.
- Antigen — Any macromolecular substance (protein, polysaccharide, or toxin), usually foreign to the body, capable of triggering a specific immune response, stimulating antibody synthesis, and reacting specifically with them. As an adjective, it describes an element possessing this immunogenic property.
- Autoagglutination — A spontaneous biological or immunological phenomenon in which blood cells (especially erythrocytes or platelets) in a sample cluster and clump together on their own, as a result of the direct reaction between membrane antigens and specific autoantibodies present in their own serum, without the addition of an external reagent; a clinical test relevant for diagnosing autoimmune hemolytic anemias.
- Self-harm — A destructive act, behavior, or impulse directed consciously or unconsciously by an individual against their own person, resulting in bodily injuries, self-mutilation, or suicide attempts. In immunology, the term metaphorically describes the pathological process where the immune system erroneously attacks the body's own healthy tissues (autoimmunity).