#agranulocit

• Agranulocyte — A type of leukocyte (white blood cell) characterized by the absence of specific granules in its cytoplasm and a non-lobed nucleus; agranulocytes include lymphocytes and monocytes, playing a vital role in adaptive immunity.
• Agranulocytic — Relating to agranulocytes or agranulocytosis; describing cellular phenomena, immune reactions, or clinical syndromes associated with white blood cells that lack specific cytoplasmic granules or with conditions marked by a severe depletion of granulocytes.
• Agranulocytosis — An acute and severe hematological condition characterized by a drastic reduction or near-complete disappearance of granulocytes (primarily neutrophils) in the peripheral blood, dropping below 500 per microliter. It leaves the body highly vulnerable to life-threatening infections.
• Aleukocytosis — A rare pathological condition characterized by the total absence or extreme, critical, and potentially fatal decrease of leukocytes (white blood cells) in the peripheral blood. It represents a severe manifestation of bone marrow aplasia or major hematopoietic disorders, exposing the organism to an imminent risk of massive opportunistic infections due to the complete collapse of the immune system.
• Amidopyrine — A medicinal compound from the pyrazolone class, historically used as a potent analgesic, antipyretic, and anti-inflammatory agent, chemically known as aminophenazone. Although it possesses high structural efficiency in combating fever and acute pain, its modern clinical use has been severely restricted or banned in most countries due to the documented risk of inducing severe agranulocytosis and the formation of carcinogenic nitrosamines in the stomach.
• Aminophenazone — An organic compound of the pyrazolone class, historically widely used as a drug with potent analgesic, antipyretic, and anti-inflammatory properties (also known as pyramidon). Due to its major structural risk of causing severe agranulocytosis and its carcinogenic potential through the formation of nitrosamines, its clinical use has been banned or severely restricted in modern medicine.