#benign

• Acanthoma — A benign cutaneous tumor formation characterized by the hyperplastic proliferation of keratinocytes within the stratum spinosum of the epidermis (acanthosis). This well-circumscribed lesion can manifest in various clinical and histological forms, the most notable being clear cell acanthoma (Degos) and acanthoma fissuratum, requiring microscopic differential diagnosis to exclude epidermal malignancies.
• Adenochondroma — A benign tumor formation with a mixed histological structure, characterized by the simultaneous proliferation of epithelial glandular tissue and cartilaginous tissue. This structural benign neoplasm occurs most frequently within the salivary glands (particularly in pleomorphic adenomas) or the mammary gland, presenting a slow evolution and sharp demarcation from surrounding tissues.
• Adenofibroma — A form of benign tumor with a mixed structure, characterized by the simultaneous and balanced proliferation of glandular epithelial elements and fibrous connective supporting tissue. This nodular lesion structurally develops most frequently within the mammary gland (where it is also known as fibroadenoma) or the ovaries, presenting upon palpation as a firm, mobile, and well-circumscribed mass.
• Adenolymphangioma — A rare form of benign tumor with a mixed structure, characterized by the simultaneous proliferation of glandular epithelial elements and encapsulated dilated lymphatic vessels. This nodular lesion structurally develops most often within regional lymph nodes or near major salivary glands (such as the parotid gland), presenting a complex microscopic appearance with lymph-filled cystic spaces.
• Adenolipomatosis — A condition characterized by the benign, simultaneous, and excessive proliferation of adipose tissue within or around lymph nodes and glandular structures, leading to a diffuse enlargement of their volume. This histopathological structural phenomenon disrupts the normal architecture of regional soft tissue, generating palpable nodular formations that are often asymptomatic but can pose differential diagnosis challenges with simple lipomas or malignant lymphadenopathies.
• Adenoma — A form of benign tumor that structurally develops from the epithelial cells of a gland or from tissues exhibiting glandular structures. Although it is non-cancerous and does not metastasize, an adenoma can cause significant clinical problems by compressing neighboring organs or through the excessive and uncontrolled secretion of hormones, as occurs in endocrine glands.
• Adenomatosis — A pathological condition characterized by the simultaneous development, excessive proliferation, or appearance of a large number of adenomas (benign tumors of an epithelial-glandular nature) within an organ or secretory tissue. This structural condition alters the normal histological architecture of the affected organ and can evolve, under certain clinical or genetic contexts, toward a malignant transformation (adenocarcinoma).
• Adenomyoma — A benign tumor formation with a mixed structure, composed of epithelial glandular elements and smooth muscle tissue. This structural benign neoplasm is most frequently encountered in the uterus, where it is considered a localized form of adenomyosis, or in the gastrointestinal tract, manifesting through pelvic pain, abnormal bleeding, or compressive symptoms.
• Adipofibroma — A benign tumor formation with a mixed histological structure, composed of a mixture of mature adipose tissue and proliferated fibrous connective tissue. This structural benign neoplasm occurs most frequently within the subcutaneous cellular tissue, internal organs, or the mediastinum, presenting a firm-elastic consistency and sharp demarcation from neighboring anatomical structures.
• Lipoma — A benign, well-circumscribed, and encapsulated tumor formation consisting of the localized proliferation of mature adipose cells; a very rare medical term used as a perfect synonym for the classic lipoma. This structural benign neoplasm develops within the subcutaneous cellular tissue or intermuscular spaces, presenting a soft, elastic consistency and a slow evolution, without tendencies for infiltration or malignancy.
• Ameloblastoma — A benign but locally invasive and aggressive tumor of odontogenic origin, developing most frequently in the mandible or maxilla from the cells of the enamel organ (ameloblasts). Although it rarely metastasizes, it carries a high rate of local recurrence if not completely excised via radical surgical resection, causing surrounding bone destruction and facial deformities.
• Angiolipoma — A benign tumorous formation of a mixed nature, structurally composed of mature adipose tissue (lipoma) and a well-defined, rich network of proliferated and often thrombosed blood vessels (angiomatous component). This histological lesion frequently occurs at the subcutaneous level, particularly on the forearms or trunk in young adults, clinically manifesting as firm, well-circumscribed nodules that, unlike classic lipomas, are often painful to the touch.
• Angioma — A benign tumorous formation or well-defined congenital malformation, developed through the abnormal proliferation and crowding of blood vessels (hemangioma) or lymphatic vessels (lymphangioma). Clinically manifested as red-purple patches or nodules on the skin, mucous membranes, or internal organs (frequently on the liver or brain), this structural element generally has a slow and non-invasive evolution but can associate bleeding risks in case of local mechanical trauma.
• Angiomyoma — A benign tumorous formation of a mixed nature, structurally composed of proliferating smooth muscle fibers and a well-defined, dense network of widened blood vessels. Clinically known also as vascular leiomyoma or angioleiomyoma, this histological lesion frequently develops within the deep dermis or subcutaneous tissue of the lower extremities in adults, manifesting as a small, firm nodule that is often painful to the touch or during temperature changes.