#alienated

• Abalienated — An archaic medical and legal term used to describe a person who has lost their mental faculties, sanity, or connection with reality; mentally alienated. In the context of historical forensic evaluations, being abalienated implied a lack of criminal responsibility and required the establishment of legal guardianship.
• Alienated — Having been legally alienated or transferred from a patrimony; an individual suffering from a severe mental disorder (insane, mentally alienated) or a person who is isolated, detached from social realities or from themselves. As a noun, the term was historically used in medicine to designate psychiatric asylum patients, and currently describes cultural estrangement.
• Alienated — A female individual suffering from a severe mental disorder characterized by the loss of discernment and contact with reality; (adjectival) completely estranged socially, culturally, or emotionally, living in deep isolation. In a strict legal context, it refers to a feminine asset, land, or property right that has been formally and legally transferred, conveyed, or sold to another party.
• Antagonized — Having undergone the process of antagonization; having been turned into an opponent or treated with hostility. In biochemistry and pharmacology, it describes a biological receptor, hormone, or enzyme whose natural activity has been completely blocked, neutralized, or inhibited through the intervention of an antagonistic chemical agent.