#acroscleroderma

• Acroscleroderma — A localized clinical form or initial stage of systemic sclerosis (scleroderma), characterized by the thickening, induration, and progressive loss of skin elasticity restricted to the distal extremities (hands, feet) and the face. This structural autoimmune process alters microcirculation and dermal connective tissue, being almost constantly associated with Raynaud's phenomenon, painful digital tip ulcers, sclerodactyly, and facial tightening.