#acropachy

• Acropachy — A rare pathological clinical syndrome characterized by the subperiosteal thickening and deformation of the long bones of the extremities, associated with soft tissue hypertrophy of the fingers and toes (clubbing / Hippocratic digits). This osteoarticular structural phenomenon occurs most frequently as an advanced extrathyroidal manifestation of Graves' disease (thyroid acropachy), typically coexisting with exophthalmos and pretibial myxedema.
• Acropachydermia — A rare pathological clinical condition, congenital or acquired, characterized by the symmetric hypertrophic thickening of the skin and soft tissues of the extremities (hands and feet), often associated with subperiosteal osteoarticular deformities of the phalanges. This severe structural phenomenon impairs cutaneous elasticity and fine joint mobility, frequently manifesting within complex neuroendocrine syndromes, such as pachydermoperiostosis (Touraine-Solente-Golé syndrome), or as a secondary paraneoplastic reaction in chronic pulmonary diseases.