Bacitracin
Definition
A broad-spectrum polypeptide antibiotic produced through biosynthesis by specific strains of Bacillus subtilis or Bacillus licheniformis. This structural pharmacological compound acts by inhibiting bacterial cell wall synthesis, being primarily used in topical applications (ointments, creams) to prevent and treat superficial skin and eye infections caused by Gram-positive bacteria.
Bilingual Equivalents
- Bacitracin
- Bacitracinum
Grammatical & Source Details
| Inflection Type | Feminine noun, standard singular usage with localized morphological adjustments. |
| Formation | Scientific term derived from the prefix 'Bacillus' and the surname 'Tracy' (the patient from whom the strain was isolated) with the standard chemical suffix '-in'. |
| Spelling / Pronunciation | [ba.t͡ʃi.tra.ˈt͡ʃi.nə] |
| Source | International Pharmacopoeia and Biochemical Lexicon |
Contextual Usage Examples
RO: Medicul dermatolog a recomandat aplicarea unui unguent ce conține bacitracină pentru a preveni suprainfectarea rănii superficiale.
EN: The dermatologist recommended applying an ointment containing bacitracin to prevent secondary infection of the superficial wound.
RO: Această bacitracină este adesea combinată cu neomicina pentru a obține un spectru antimicrobian extins în preparatele topice.
EN: This bacitracin is often combined with neomycin to achieve an extended antimicrobial spectrum in topical preparations.
RO: Deoarece prezintă o toxicitate renală ridicată la administrarea sistemică, utilizarea de bacitracină este restricționată la calea locală.
EN: Because it presents high renal toxicity upon systemic administration, the use of bacitracin is restricted to the local route.
Idioms & Phrases
Unguent cu bacitracină / Bacitracin ointment
RO: Preparat farmaceutic semisolid utilizat local pe piele pentru distrugerea bacteriilor patogene din zgârieturi sau tăieturi.
EN: A semisolid pharmaceutical preparation used locally on the skin to destroy pathogenic bacteria in scratches or cuts.
Combinație cu bacitracină / Bacitracin combination
RO: Formulă medicamentoasă structurală care asociază mai multe antibiotice complementare pentru a mări eficiența clinică.
EN: A structural drug formulation that associates multiple complementary antibiotics to increase clinical efficacy.
Rezistență la bacitracină / Bacitracin resistance
RO: Capacitate dobândită a unor tulpini bacteriene de a supraviețui și de a se multiplica în prezența acestui antibiotic.
EN: An acquired capacity of certain bacterial strains to survive and multiply in the presence of this antibiotic.
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