Autoradiography
Definition
A biophysical method of investigation and structural imaging consisting of detecting and recording the spatial distribution of radioactive substances or isotope-labeled molecules (tracers), by directly exposing the biological or metallurgical sample onto a photographic emulsion or a digital sensor. This experimental process utilizes the self-emission of radiation (alpha, beta, or gamma) from the sample to expose the contact medium, serving as a fundamental technique in nucleic acid mapping, cellular metabolism studies, and protein localization.
Bilingual Equivalents
- Autoradiography
- Radioautography
Grammatical & Source Details
| Inflection Type | Feminine noun, regular structural variations for both numbers. |
| Formation | Scientific compound derived from French 'autoradiographie', combining the prefixes 'auto-' and 'radio-' with the functional suffix base '-graphy'. |
| Spelling / Pronunciation | [ˌɔː.toʊ.reɪ.di.ˈɒɡ.rə.fi] |
| Source | Principles of Instrumental Analysis and Textbook of Molecular Cell Biology Methods |
Contextual Usage Examples
RO: Profesorul a explicat cum tehnica de autoradiografie a permis determinarea exactă a modului de replicare a moleculei de ADN.
EN: The professor explained how the autoradiography technique allowed the exact determination of the DNA molecule's replication mode.
RO: Această autoradiografie modernă folosește ecrane digitale cu fosfor pentru a reduce timpul de expunere al probelor biologice.
EN: This modern autoradiography utilizes digital phosphor screens to reduce the exposure time of biological samples.
RO: Prin autoradiografie, cercetătorii au demonstrat stocarea preferențială a compusului chimic în celulele hepatice.
EN: Through autoradiography, researchers demonstrated the preferential storage of the chemical compound within hepatic cells.
Idioms & Phrases
Tehnică de autoradiografie / Autoradiography technique
RO: Protocol biofizic experimental bazat pe auto-impresionarea unei emulsii fotografice prin emisiile nucleare ale eșantionului marcat.
EN: An experimental biophysical protocol based on the self-exposure of a photographic emulsion via the nuclear emissions of the labeled sample.
Autoradiografie cantitativă / Quantitative autoradiography
RO: Metodă avansată de măsurare a densității optice pe film pentru a determina concentrația exactă a izotopilor dintr-o secțiune tisulară.
EN: An advanced method of measuring optical density on film to determine the exact isotope concentration within a tissue section.
Autoradiografie la nivel celular / Microscopic autoradiography
RO: Aplicație microscopică fină ce permite vizualizarea trasorilor radioactivi direct la nivelul organitelor din citoplasmă.
EN: A fine microscopic application allowing the visualization of radioactive tracers directly at the level of cytoplasmic organelles.
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