Autopepsia

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feminine noun (medicine / pathophysiology)

Definition

Spontaneous self-digestion of an organ's tissues (especially the gastric mucosa or the pancreas) caused by its own enzymatic secretions or digestive juices, due to pathological disruptions of cellular protective mechanisms or following post-mortem necrosis. In gastroenterology, this destructive structural phenomenon forms the basis for the onset of perforating peptic ulcers or acute necrotizing-hemorrhagic pancreatitis.

Bilingual Equivalents

  • Autopepsia
  • Autodigestion

Grammatical & Source Details

Inflection Type Feminine noun, regular structural variations for both numbers.
Formation Medical term derived from the Greek components 'auto-' (self) and the digestional suffix base '-pepsia'.
Spelling / Pronunciation [ˌɔː.toʊ.pep.ˈsi.ə]
Source Gastroenterology Lexicon and Pathological Systems Textbook

Contextual Usage Examples

RO: În pancreatita acută, activarea timpurie a tripsinei în interiorul glandei declanșează un proces sever de autopepsie.

EN: In acute pancreatitis, the early activation of trypsin inside the gland triggers a severe process of autopepsia.

RO: Diminuarea stratului protector de mucus gastric expune celulele epiteliale riscului de autopepsie sub acțiunea acidului clorhidric.

EN: The reduction of the protective gastric mucus layer exposes epithelial cells to the risk of autopepsia under the action of hydrochloric acid.

RO: Medicul legist a explicat că modificările structurale ale stomacului observate la autopsie sunt rezultatul unei autopepsii post-mortem.

EN: The forensic pathologist explained that the structural changes of the stomach observed at autopsy are the result of a post-mortem autopepsia.

Idioms & Phrases

Autopepsie gastrică / A pathological process whereby gastric juice attacks and erodes the stomach wall due to the collapse of alkaline cellular barriers.

RO: Proces patologic prin care sucul gastric atacă și erodează peretele stomacului din cauza prăbușirii barierelor celulare alcaline.

Autopepsie enzimatică / Massive destruction of an organ's parenchyma caused by the uncontrolled release of its own active hydrolases into the tissues.

RO: Distrugere masivă a parenchimului unui organ provocată de eliberarea necontrolată a propriilor hidrolaze active în țesuturi.

Fenomen de autopepsie post-mortem / A spontaneous chemical decomposition of abdominal organs that begins immediately after death under the influence of their own enzymes.

RO: Modificare chimică spontană de descompunere a organelor abdominale care începe imediat după deces sub influența propriilor enzime.

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