Angiosarcoma

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neuter noun (medicine / pathology / oncology)

Definition

A highly aggressive and rare malignant tumorous formation, developed through the chaotic and atypical proliferation of endothelial cells lining the interior of blood vessels or lymphatic vessels. This well-defined structural oncological lesion can appear in any region of the body, but frequently affects the skin (especially the scalp), subcutaneous tissue, breast, liver, or spleen, being characterized by rapid progression, deep local infiltration, and a high rate of early metastasis.

Bilingual Equivalents

  • Angiosarcoma
  • Malignant vascular tumor

Grammatical & Source Details

Inflection Type Neuter noun, regular structural plural shifting to '-oame' and standard case endings.
Formation Neologistic compound formed structurally from the scientific combining elements of Greek origin 'angio-' (vessel) and 'sarcoma' (malignant tumor developed from connective tissue).
Spelling / Pronunciation [an.dʒi.o.sar.ˈkom]
Source Official Compendium of Malignant Soft Tissue Tumors and Pathological Classifications

Contextual Usage Examples

RO: Examenul histopatologic al biopsiei cutanate a confirmat prezența unui angiosarcom cutanat cu grad înalt de malignitate.

EN: The histopathological examination of the skin biopsy confirmed the presence of a cutaneous angiosarcoma with a high grade of malignancy.

RO: Pacientul diagnosticat cu angiosarcom hepatic a început imediat un protocol agresiv de chimioterapie și radioterapie.

EN: The patient diagnosed with hepatic angiosarcoma immediately started an aggressive chemotherapy and radiotherapy protocol.

RO: O rezecție chirurgicală extinsă este esențială în cazul unui angiosarcom pentru a asigura margini de siguranță oncologică negative.

EN: An extensive surgical resection is essential in the case of an angiosarcoma to ensure negative oncological safety margins.

Idioms & Phrases

Angiosarcom cutanat / Cutaneous angiosarcoma

RO: Formă clinică ce apare predominant pe fața și scalpul persoanelor vârstnice sub forma unor plăci sau noduli purpurii cu creștere rapidă.

EN: A clinical form appearing predominantly on the face and scalp of elderly individuals as rapidly growing purplish plaques or nodules.

Angiosarcom hepatic / Hepatic angiosarcoma

RO: Tumoră malignă rară a ficatului, cu prognostic sever, asociată istoric cu expunerea la dioxid de thoriu sau clorură de vinil.

EN: A rare malignant tumor of the liver, with a severe prognosis, historically associated with exposure to thorium dioxide or vinyl chloride.

Profil histologic de angiosarcom / Angiosarcoma histological profile

RO: Ansamblul trăsăturilor microscopice din laborator caracterizat prin canale vasculare anastamozate neregulate tapetate de celule endoteliale atipice.

EN: The set of microscopic laboratory features characterized by irregular anastomosing vascular channels lined by atypical endothelial cells.

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