Anaplastic
Definition
Pertaining to or characterized by anaplasia; exhibiting a total or partial loss of cellular differentiation and normal structural orientation within a tissue. In oncology, the term describes highly aggressive malignant tumors (such as anaplastic thyroid carcinoma or anaplastic astrocytoma), whose cells have reverted to a primitive, embryonic stage, displaying a very high division rate and an increased resistance to standard treatments.
Bilingual Equivalents
- Anaplastic
- Undifferentiated
Grammatical & Source Details
| Inflection Type | Variable adjective with standard masculine, feminine, and structural plural variations. |
| Formation | Adapted from international scientific roots used to describe cellular dedifferentiation states and tumor traits. |
| Spelling / Pronunciation | [ˌæn.ə.ˈplæs.tɪk] |
| Source | WNM Clinical Pathology Standard Definitions and Cancer Taxonomy |
Contextual Usage Examples
RO: Examenul histopatologic a relevat prezența unui carcinom anaplastic, determinând echipa medicală să acționeze rapid.
EN: The histopathological examination revealed the presence of an anaplastic carcinoma, prompting the medical team to act quickly.
RO: Celulele de tip anaplastic își pierd capacitatea de a îndeplini funcțiile specifice țesutului din care provin.
EN: Anaplastic-type cells lose their ability to perform the specific functions of the tissue from which they originate.
RO: Un gliom anaplastic reprezintă o formă avansată de tumoră cerebrală ce necesită o abordare terapeutică complexă.
EN: An anaplastic glioma represents an advanced form of brain tumor that requires a complex therapeutic approach.
Idioms & Phrases
Carcinom tiroidian anaplastic / Anaplastic thyroid carcinoma
RO: O formă rară și extrem de agresivă de cancer de tiroidă, caracterizată prin creșterea rapidă a unei mase tumorale cervicale.
EN: A rare and highly aggressive form of thyroid cancer, characterized by the rapid growth of a cervical tumor mass.
Limfom anaplastic cu celule mari / Anaplastic large-cell lymphoma
RO: Tip de limfom non-Hodgkin cu celule T agresive, definit structural prin prezența unor limfocite anormale mari.
EN: A type of aggressive T-cell non-Hodgkin lymphoma, structurally defined by the presence of large abnormal lymphocytes.
Variantă anaplastică / Anaplastic variant
RO: Subtip tumoral care indică o malignitate superioară și un prognostic mai rezervat în ghidurile de clasificare clinică.
EN: A tumor subtype indicating higher malignancy and a more guarded prognosis in clinical classification guidelines.
Latest Contextual News
No recent news found for this topic.