Amyelia
Definition
An extremely rare and severe congenital malformation within the neural tube defects spectrum, characterized by the total absence or complete developmental arrest of the spinal cord. This severe structural anomaly occurs during the first weeks of embryogenesis due to the failure of the posterior neuropore to close, being incompatible with extrauterine life and often associated with other major cranial malformations.
Bilingual Equivalents
- Amyelia
- Amyely
Grammatical & Source Details
| Inflection Type | Feminine noun, standard structural plural variations for embryological pathologies. |
| Formation | Derived from the ancient Greek combining form using the privative prefix 'a-' (without) and the anatomical root 'myelos' (marrow/spinal cord). |
| Spelling / Pronunciation | [eɪ.maɪ.ˈiː.li.ə] |
| Source | International Classification of Diseases and Teratological Nomenclature |
Contextual Usage Examples
RO: În cadrul ecografiei morfologice de prim trimestru, medicul specialist poate detecta semnele timpurii ale unei patologii de tip amielie.
EN: During the first-trimester morphological ultrasound, the specialist physician can detect the early signs of an amyelia-type pathology.
RO: Studiile de genetică medicală sugerează că apariția unei caz de amielie poate fi influențată de deficitul sever de acid folic matern.
EN: Medical genetics studies suggest that the occurrence of an amyelia case can be influenced by severe maternal folic acid deficiency.
RO: Autopsia anatomo-patologică a confirmat diagnosticul de amielie totală, asociată structural cu o formă severă de anencefalie.
EN: The anatomo-pathological autopsy confirmed the diagnosis of total amyelia, structurally associated with a severe form of anencephaly.
Idioms & Phrases
Amielie totală / Total amyelia
RO: Formă clinică extremă în care întreaga structură nervoasă a măduvei spinării lipsește de-a lungul întregului canal vertebral.
EN: An extreme clinical form in which the entire nervous structure of the spinal cord is missing along the whole vertebral canal.
Amielie parțială / Partial amyelia
RO: Defect congenital localizat în care aplazia medulară afectează doar un segment structural specific (lombar sau sacrat) al coloanei.
EN: A localized congenital defect where the spinal aplasia affects only a specific structural segment (lumbar or sacral) of the column.
Spectru teratologic de amielie / Amyelia teratological spectrum
RO: Grup de anomalii neuro-anatomice majore caracterizate prin distrugerea sau absența parțială ori totală a țesutului medular primitiv.
EN: A group of major neuro-anatomical anomalies characterized by the destruction or partial or total absence of the primitive medullary tissue.
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