Amidase
Definition
An enzyme belonging to the hydrolase class that catalyzes the hydrolytic cleavage of a linear amide bond, converting an amide compound into a carboxylic acid and ammonia or a corresponding amine. This biocatalyst plays an essential structural role in nitrogen metabolism, cellular detoxification processes, and industrial biocatalysis used for the enantioselective synthesis of high-purity pharmaceutical compounds.
Bilingual Equivalents
- Amidase
- Amidohydrolase
Grammatical & Source Details
| Inflection Type | Feminine noun, regular biochemical terminology variations. |
| Formation | Derived from the chemical root 'amide' utilizing the standard functional enzymatic suffix '-ase'. |
| Spelling / Pronunciation | [ə.mi.ˈdeɪs] |
| Source | International Union of Biochemistry and Molecular Biology Lexicon |
Contextual Usage Examples
RO: Cercetătorii au izolat o tulpină bacteriană capabilă să producă o amidază termostabilă, extrem de utilă în epurarea apelor reziduale industriale.
EN: The researchers isolated a bacterial strain capable of producing a thermostable amidase, highly useful in industrial wastewater treatment.
RO: O activitate scăzută a enzimei amidază în organism poate genera acumulări toxice de metaboliți pe bază de azot în țesuturi.
EN: A low activity of the amidase enzyme in the body can generate toxic accumulations of nitrogen-based metabolites in tissues.
RO: Ingineria genetică permite optimizarea structurii de amidază pentru a crește viteza de sinteză a antibioticelor moderne.
EN: Genetic engineering allows the optimization of the amidase structure to increase the synthesis rate of modern antibiotics.
Idioms & Phrases
Activitate amidază / Amidase activity
RO: Unitate de măsură cinetică ce exprimă cantitatea de substrat amidic hidrolizat de către enzimă într-un interval fix de timp.
EN: A kinetic unit of measurement expressing the amount of amide substrate hydrolyzed by the enzyme within a fixed time interval.
Amidază bacteriană / Bacterial amidase
RO: Enzimă extrasă din microorganisme utilizată pe scară largă ca biocatalizator în bioremedierea solurilor contaminate cu pesticide.
EN: An enzyme extracted from microorganisms widely used as a biocatalyst in the bioremediation of soils contaminated with pesticides.
Inhibitor de amidază / Amidase inhibitor
RO: Compus chimic specific care blochează situl activ al enzimei, oprind degradarea substraturilor amidice țintă.
EN: A specific chemical compound that blocks the active site of the enzyme, halting the degradation of target amide substrates.
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