Allotype

⭐⭐
masculine / neuter noun (genetics / immunology)

Definition

A genetic variation or structural antigenic determinant within a protein or immunoglobulin (antibody) that differentiates individuals within the same species. This form of molecular polymorphism reflects the presence of different alleles at the corresponding gene locus, utilized as an essential biological marker in population genetics, forensics, and immunogenetics.

Bilingual Equivalents

  • Allotype
  • Allotypy marker

Grammatical & Source Details

Inflection Type Neuter/masculine abstract noun, following standard morphosyntactic configurations for plural and case structural shifts.
Formation Neoclassical scientific compound combining the prefix 'allo-' (different) with the structural suffix '-type' (form/model).
Spelling / Pronunciation [ˈæ.loʊ.ˌtaɪp]
Source Encyclopedia of Medical Immunology, Molecular Pathology, and Forensic Serology

Contextual Usage Examples

RO: Cercetătorul a identificat un alotip rar al lanțului greu de imunoglobulină G în probele de sânge recoltate.

EN: The researcher identified a rare allotype of the immunoglobulin G heavy chain in the collected blood samples.

RO: Analiza unui alotip structural specific permite determinarea paternității cu o acuratețe statistică remarcabilă în medicina legală.

EN: Analyzing a specific structural allotype allows paternity determination with remarkable statistical accuracy in forensic medicine.

RO: Fiecare alotip identificat a fost catalogat într-o bază de date internațională pentru a monitoriza diversitatea genetică umană.

EN: Each identified allotype was cataloged in an international database to monitor human genetic diversity.

Idioms & Phrases

Alotip de imunoglobulină / Immunoglobulin allotype

RO: Variație secvențială de aminoacizi în regiunea constantă a anticorpilor, transmisă ereditar conform legilor mendeliene.

EN: A sequential amino acid variation in the constant region of antibodies, inherited according to Mendelian laws.

Marker de alotip / Allotype marker

RO: Indicator molecular structural utilizat în serologie pentru a diferenția grupurile serologice în cadrul transfuziilor de sânge.

EN: A structural molecular indicator used in serology to differentiate serological groups within blood transfusions.

Alotip structural proteic / Structural protein allotype

RO: Configurație atomică tridimensională a unei proteine serice care determină proprietățile sale antigenice specifice la individ.

EN: A three-dimensional atomic configuration of a serum protein that determines its specific antigenic properties in the individual.

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