Acrosclerosis
Definition
An indurative pathological process or condition characterized by the sclerosis, thickening, and hardening of the connective tissue and skin at the distal extremities of the limbs (digits, hands) and the face, appearing as a major manifestation within limited systemic scleroderma. The term is often used interchangeably with acroscleroderma, structurally highlighting the dense fibrosis and tightening of periarticular and dermal collagen.
Bilingual Equivalents
- Acrosclerosis
- Sclerodactyly (parțial)
Grammatical & Source Details
| Inflection Type | Feminine noun with regular morphological structural plural modifications in '-oze'. |
| Formation | Learned compound combining 'acro-' (extremity) with the pathological noun 'sclerosis' (hardening/induration). |
| Spelling / Pronunciation | [a.kro.skle.ˈro.zə] |
| Source | Lexicon of Advanced Rheumatoid Diseases and Collagen Morphologies |
Contextual Usage Examples
RO: Instalarea unei forme de acroscleroză rigidizează degetele în flexie, determinând apariția aspectului de gaură sau gheară.
EN: The onset of a form of acrosclerosis stiffens the fingers in flexion, causing the appearance of a claw hand.
RO: Radiografia a evidențiat calcificări periarticulare subcutanate secundare acestui proces de acroscleroză cronică.
EN: The X-ray revealed subcutaneous periarticular calcifications secondary to this chronic acrosclerosis process.
RO: Medicul reumatolog monitorizează extinderea leziunilor de acroscleroză pentru a evalua riscul de afectare a organelor interne.
EN: The rheumatologist monitors the spread of acrosclerosis lesions to evaluate the risk of internal organ involvement.
Idioms & Phrases
Acroscleroză cutanată / Cutaneous acrosclerosis
RO: Indurarea structurală a straturilor pielii de la nivelul falangelor, care devin lucioase, tensionate și imposibil de pliat.
EN: The structural induration of skin layers at the phalanges, which become shiny, taut, and impossible to pinch.
Proces de acroscleroză / Process of acrosclerosis
RO: Succesiunea modificărilor biochimice prin care fibrele de colagen se multiplică patologic, sufocând capilarele distale.
EN: The sequence of biochemical changes through which collagen fibers multiply pathologically, suffocating distal capillaries.
Acroscleroză cu calcinoză / Acrosclerosis with calcinosis
RO: Asociere clinică în care indurarea fibroasă a degetelor este complicată de precipitarea cristalelor de calciu sub piele.
EN: A clinical association where the fibrotic induration of the fingers is complicated by the precipitation of calcium crystals under the skin.
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