DEX » Lexicon of Clinical Gastroenterology and Pathological Terms » aclorhidrie

Achlorhydria

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noun (medicine / pathology / gastroenterology)

Definition

A severe pathological condition defined by the complete absence of hydrochloric acid in the gastric juice. This dysfunction disrupts the normal activation of digestive enzymes, compromises the sterilization of ingested food, and impairs the absorption of vital micronutrients, often associated with autoimmune atrophic gastritis or long-term use of proton pump inhibitors.

Bilingual Equivalents

  • Achlorhydria
  • Gastric anacidity

Grammatical & Source Details

Inflection Type Feminine noun, standard singular usage, definite form: aclorhidria, genitive/dative: aclorhidriei.
Formation Neologistic loan from French ('achlorhydrie'), composed of the Greek privative prefix 'a-' combined with hydrochloric root elements.
Spelling / Pronunciation [a.klor.hi.ˈdri.e]
Source Lexicon of Clinical Gastroenterology and Pathological Terms

Contextual Usage Examples

RO: Diagnosticul de aclorhidrie a fost confirmat după efectuarea unui test de monitorizare a pH-ului gastric pe parcursul a 24 de ore.

EN: The diagnosis of achlorhydria was confirmed after performing a 24-hour gastric pH monitoring test.

RO: Din cauza unei stări avansate de aclorhidrie, pacientul a dezvoltat o anemie severă prin malabsorbția vitaminei B12.

EN: Due to an advanced state of achlorhydria, the patient developed severe anemia through the malabsorption of vitamin B12.

RO: Medicul a explicat că această aclorhidrie cronică favorizează dezvoltarea unei flore bacteriene dăunătoare în interiorul stomacului.

EN: The doctor explained that this chronic achlorhydria favors the development of harmful bacterial flora inside the stomach.

Idioms & Phrases

Aclorhidrie absolută / Absolute achlorhydria / refractory achlorhydria

RO: Absența completă și ireversibilă a secreției de acid gastric, care nu răspunde nici măcar la stimularea chimică maximă cu histamină.

EN: The complete and irreversible absence of gastric acid secretion, which does not respond even to maximal chemical stimulation with histamine.

Aclorhidrie secundară / Secondary achlorhydria

RO: Lipsa acidului clorhidric provocată de factori externi, cum ar fi intervențiile chirurgicale gastrice sau medicația antiacidă prelungită.

EN: The lack of hydrochloric acid caused by external factors, such as gastric surgical interventions or prolonged antacid medication.

Sindrom de aclorhidrie / Achlorhydria syndrome

RO: Complex de simptome digestive (balonare, indigestie, diaree) corelate cu inabilitatea stomacului de a genera mediu acid.

EN: A complex of digestive symptoms (bloating, indigestion, diarrhea) correlated with the stomach's inability to generate an acidic environment.

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