#weakening

• Debilitation — The act of weakening or bringing into a state of asthenia and its result; the physiological or psychological process through which an organism is reduced to a state of profound weakness, chronic exhaustion, or loss of vital strength, as a consequence of overwork, disease, or unfavorable environmental factors.
• Enervation — The act of enervating or bringing into a state of asthenia and its result; the medical, physiological, or psychological process through which an organism is reduced to a state of exhaustion, profound weakness, or loss of vital energy; physical or nervous overwork caused by pathogenic factors, stress, or overloading effort.