#nail matrix defect

• Anonychia — A rare congenital anomaly or acquired pathological condition characterized by the complete absence of one or more nails from the fingers or toes. This structural defect stems from a developmental failure of the nail matrix during the fetal stage or its subsequent destruction due to severe trauma, infections, or systemic dermatological diseases, frequently serving as a clinical marker within complex genetic syndromes such as ectodermal dysplasia.