#exacerbation

• Exacerbation — The act of exacerbating and its result; a sudden and pronounced worsening of the course of a chronic disease or a conflictual situation. In medical terminology, it represents a violent relapse or an intense clinical flare-up that interrupts a period of remission, often requiring emergency therapeutic intervention or immediate hospitalization.
• Aggravation — The act of worsening and its result; the process of progressive deterioration, complication, or exacerbation of a health status, a legal conflict, or a financial crisis. In a clinical context, it represents the transition of a set of symptoms from a stable or moderate stage to a severe or critical one, often requiring urgent therapeutic intervention.